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Welcome to my site! Youth vaping is undeniably a public health crisis and I have seen consequences unfold in my middle school. One of the biggest issues is that youth who vape are either not aware of the health consequences or simply unconvinced by the educational outreach material.
Moreover, because e-cigarettes are a relatively new and unregulated market, we're still lacking a comprehensive understanding of the changes occurring at the cellular level. Ultimately, I want to help raise awareness that vaping is harmful and leads to life-long consequences.
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- Angelin Mathew :)
Hypothesis:
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The framework I developed is able to [1] identify overall (global) endothelial cell gene expression differences between JUUL smokers and non-smokers, [2] rank differentially expressed genes, [3] characterize biological products of the sequences, [4] and characterize altered cellular pathways.
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In particular, I hypothesized differential expression would be noted highest in genes relating to fibrosis, DNA repair, and inflammation.
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